The organic anion transporter oat family
WebbOrganic anion transporters (OATs) and organic cation transporters (OCTs) are members of the superfamily of transporters, Slc (solute carriers). Most are in the families Slc21 … WebbThe organic anion transporter (OAT) subfamily, which constitutes roughly half of the SLC22 (solute carrier 22) transporter family, has received a great deal of attention …
The organic anion transporter oat family
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WebbSchnabolk, G. W., Youngblood, G. L., & Sweet, D. H. (2006). Transport of estrone sulfate by the novel organic anion transporter Oat6 (Slc22a20). Webb214 rader · Organic anion transporting polypeptides (OATPs in humans, Oatps in rodents) are multispecific transporters located in numerous epithelia throughout the body. They …
Webb11 apr. 2024 · Glycine synthase (AMT), a solute organic anion transporter family member (OAT), and fatty acyl-coA reductase (FAR) are predicted to be regulated by multiple … Webb1 aug. 2001 · The organic anion transporter (OAT) family handles a wide variety of clinically important compounds (antibiotics, nonsteriodal anti-inflammatory drugs, etc.) …
WebbMentioning: 17 - The aim of this study was to explore whether rhein could enhance the effects of pemetrexed (PTX) on the therapy of non-small-cell lung cancer (NSCLC) and to clarify the associated molecular mechanism. Our study shows that rhein in combination with PTX could obviously increase the systemic exposure of PTX in rats, which would be … The organic anion transporter 1 (OAT1) also known as solute carrier family 22 member 6 (SLC22A6) is a protein that in humans is encoded by the SLC22A6 gene. It is a member of the organic anion transporter (OAT) family of proteins. OAT1 is a transmembrane protein that is expressed in the brain, the placenta, the eyes, smooth muscles, and the basolateral membrane of proximal tubular cells o…
WebbMany UTs and drugs administered to CKD patients are organic anions, which are physiologically eliminated by the organic anion transporter (OAT) system [6,7]. OATs …
WebbWe explored an atenolol transporter from among the cation or anion transporters. • OCT1 expressed on apical side in enterocytes has transport activity of atenolol. • Transport of … how do you want others to see your brandWebbOATs are multispecific organic anion transporters, the substrates of which include both endogenous (e.g. cyclic nucleotides, prostaglandins, urate, dicarboxylates) and … how do you want to be managedWebb23 juni 2000 · The OAT family represents mainly the renal secretory and reabsorptive pathway for organic anions and is also involved in the distribution of organic anion in the … how do you want to be perceived as a leaderWebbMentioning: 17 - The aim of this study was to explore whether rhein could enhance the effects of pemetrexed (PTX) on the therapy of non-small-cell lung cancer (NSCLC) and … how do you want to back up your recovery keyWebbOATs are multispecific organic anion transporters, the substrates of which include both endogenous (e.g. cyclic nucleotides, prostaglandins, urate, dicarboxylates) and … how do you want to be treatedWebbThe organic anion transporters ( OAT s), part of the SLC22 superfamily of transporters, are expressed throughout the body. However, the most clinically relevant members of this … how do you want to be perceived at workWebb1 juni 2000 · Organic anion transporter (OAT) is an heterogenous family of negatively charged proteins, mainly located in kidneys and the liver, but OAT1/OAT3 are also found … how do you want to be recognized