WebbJanssen has conducted clinical trials of Simponi as a potential treatment for a number of conditions, including ankylosing spondylitis. The results of a Phase 3 clinical trial ( NCT00265083) prompted the U.S. Food and Drug Administration to approve it as an ankylosing spondylitis treatment. The 14-week trial assessed the therapy’s safety and ... WebbResults: At randomization, 138, 140, and 78 patients were assigned to the 50-mg, 100-mg, and placebo groups, respectively. After 14 weeks, 59.4%, 60.0%, and 21.8% of patients, respectively, were ASAS20 responders (P < 0.001). A 40% improvement in the ASAS criteria at week 24 occurred in 43.5%, 54.3%, and 15.4% of patients, respectively.
Living with Ankylosing Spondylitis SIMPONI® (golimumab)
WebbAbstract. As part of the National Institute for Health and Clinical Excellence (NICE) single technology appraisal (STA) process, the Evidence Review Group (ERG) produced a report to comment on the clinical and cost effectiveness of golimumab (Simponi (®), Merck Sharp & Dohme) for the treatment of ankylosing spondylitis (AS) relative to other ... Webb† SIMPONI ®, Humira ®, and Enbrel ® are also available in a prefilled syringe. Humira ® is indicated for reducing signs and symptoms in adult patients with active ankylosing spondylitis (AS). Enbrel ® is indicated … ear wax removal pregnancy
Golimumab User Reviews for Ankylosing Spondylitis
Webb14.3 Ankylosing Spondylitis. The safety and efficacy of SIMPONI were evaluated in a multicenter, randomized, double-blind, placebo-controlled trial in 356 adult patients with active ankylosing spondylitis according to modified New York criteria for … WebbFor adults with active ankylosing spondylitis (AS): Once you and your doctor are comfortable with the self-injection process, you will inject SIMPONI ® under the skin, just once a month Just One Injection, Once a Month Keep in mind that, while how often you take a medicine matters, there are other important factors to consider. WebbSimponi has an average rating of 6.0 out of 10 from a total of 102 reviews on Drugs.com. 52% of reviewers reported a positive experience, while 33% reported a negative … cts optic