High theophylline levels

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August undefined, 2024

WebHigh-carbohydrate, low-protein diets can increase theophylline activity and side effects. Sustained-release forms of theophylline should be taken on an empty stomach and should not be crushed or chewed. Liquid and non-sustained release theophylline products are best taken on an empty stomach, but they may be taken with food if stomach upset occurs. WebHigh blood theophylline levels can lead to symptoms of toxicity (see below). Therefore, theophylline blood levels are monitored periodically during treatment to assure achievement of optimal and safe levels. The initial dose is 300-600 mg once daily or as a divided dose for 3 days. The maintenance dose is 400-600 mg daily.

Theophylline (Oral Route) Side Effects - Mayo Clinic

WebIn most individuals, a plasma-theophylline concentration of 10–20 mg/litre (55–110 micromol/litre) is required for satisfactory bronchodilation, although a lower plasma … WebSep 21, 2024 · If administering aminophylline, the dose should increase by 25% (as aminophylline is 79% to 86% theophylline). Dose calculations … greatest truth never told youtube

Slo-phyllin (Theophylline, Anhydrous): Uses, Dosage, Side ... - RxList

WebTHEOPHYLLINE AS A BRONCHODILATOR. Traditionally, theophylline was used as a bronchodilator in the treatment of airway disease but, to achieve significant bronchodilatation comparable with that of a β 2 agonist, relatively high plasma concentrations are needed (10–20 mg/l). Theophylline relaxes human airway smooth … WebFactor which increase the half life include heart failure, cirrhosis, viral infection and drugs like cimetidine, ciprofloxacin, erythromycin and the oral contraceptive pill. The half life is decreased by smoking, heavy drinking and drugs like phenytoin, carbamazepine, rifampicin and barbiturates. WebNo food or liquid (other than water) was allowed for 4 hours after which a standard lunch was served. Mean peak theophylline serum levels (C max) was 6.69 mcg/mL and mean time of peak serum concentration (T ... In patients with high theophylline clearance and half-lives of about 4 to 5 hours, such as children age 1 to 9 years, the trough serum ... greatest trumpet players ever

Trental (Pentoxifylline): Uses, Dosage, Side Effects ... - RxList

WebToxic side effects of elevated theophylline levels range from minor symptoms to life-threatening complications. We investigated the incidence of life-threatening events in … WebTherapeutic levels: 4 to 12 mcg/ml [SI: 17 to 51 micromole/L] Note: 4 to 8 mcg/mL if patient is receiving other anticonvulsants. Half-life: 8 - 60 hours in adults Epoxide metabolite: 25 to 43 hours (active metabolite) Time to … flippin sweet napoleon dynamite shirtWebAug 31, 2024 · High-risk cases include the following: Acute overdose with theophylline levels higher than 80 mcg/mL Chronic toxicity with levels higher than 40 mcg/mL Patients … greatest trucking songs

"WebMar 18, 2010 · Theophylline (3-methyxanthine) has been used to treat airway diseases for over 70 years. It was originally used as a bronchodilator but the relatively high doses required are associated with frequent side effects, so its use declined as inhaled β2-agonists became more widely used. " - High theophylline levels

High theophylline levels

WebMany factors affect the rate of theophylline metabolism. Concentrations are increased in heart failure, cirrhosis, viral infections and in the elderly, and decreased in smokers, …

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WebMar 22, 2024 · Theophylline: Although causality has not been established, concurrent use of pentoxifylline with theophylline has resulted in elevated theophylline plasma levels, which may enhance the possibility of adverse effects. Drug-Food Interactions. Interactions with food have not been established. Drug-Herb Interactions WebOct 4, 2024 · In patients with theophylline overdose who are at high risk for theophylline-induced seizures, e.g., patients with acute overdoses and serum theophylline concentrations > 100 mcg/mL or chronic overdosage in patients > 60 years of age with serum theophylline concentrations > 30 mcg/mL, the need for anticonvulsant therapy should be anticipated ...

WebTheophylline levels In most individuals a plasma theophylline of between 10-20mg/litre is required for satisfactory bronchodilation; however, a lower plasma theophylline … WebMar 1, 2024 · At serum Theophylline concentrations > 20 mcg/mL, both the frequency and severity of adverse reactions increase. In general, maintaining peak serum Theophylline concentrations between 10 mcg/mL and 15 …

WebJul 18, 2024 · In high doses, theophylline can cause irritability, tremors and seizures as well as tachycardia, cardiac arrhythmias and sudden death. With the development of safer, better tolerated and more effective inhaled … WebJun 30, 2024 · Adults are may be given about 300-600mg of Theophylline per day depending on their condition. This amount is equivalent to the therapeutic dose which is between 10-20mg/L. If the amount of 25mg/L, it …

WebSafe levels for people taking theophylline are often 8 to 20 mcg/mL. Levels above 20 mcg/mL may be harmful and can happen if people take too many pills within a short time period. Such cases might include accidentally taking extra pills or having a prescription that was written for too high a dose.

WebSafe levels for people taking theophylline are often 8 to 20 mcg/mL. Levels above 20 mcg/mL may be harmful and can happen if people take too many pills within a short time … flippin the bird 2023WebThe adverse effects of theophylline include: Gastrointestinal disorders such as nausea, vomiting, gastro-oesophageal reflux. Neurological disorders such as tremor, headache, dizziness, central nervous system stimulation, insomnia, and convulsion (rare). Psychiatric disorders such as anxiety. flippin trenchingWebFeb 10, 2024 · The reference therapeutic ranges of theophylline are listed below. Reference ranges of theophylline in the treatment asthma vary by age, as follows: Adults: 5-15 µg/mL. Children: 5-10 µg/mL. The... The assessment and diagnosis of exercise-induced bronchoconstriction is made … flippin things for saleWebJul 11, 2024 · Theophylline levels: Serum theophylline levels should be monitored after initiation of therapy, prior to making dose increases; in the presence of signs or symptoms of toxicity; ... • High blood sugar like confusion, fatigue, increased thirst, increased hunger, passing a lot of urine, flushing, fast breathing, or breath that smells like fruit ... flippin twitWebAug 31, 2024 · high blood sugar--increased thirst, increased urination, dry mouth, fruity breath odor. Serious side effects may be more likely in older adults. Common side effects … greatest trumpet players listWebDec 24, 2024 · Aminophylline is FDA-approved to treat reversible airway obstruction due to asthma or other chronic lung diseases. This activity illustrates the indications, mechanism of action, pharmacokinetics, and … flippin the scriptWebTheophylline metabolism can be altered by a variety of abnormal physiologic states as well as by exogenous factors. Adult studies demonstrate a significant influence of dietary composition on theophylline biotransformation. ... Compared to the normal diet, high protein diet markedly decreased the half-life, and high carbohydrate diet greatly ... flippin the script fishing