WebSep 11, 2024 · Introduction Association between elevated cytokeratin 18 (CK-18) levels and hepatocyte death has made circulating CK-18 a candidate biomarker to differentiate non-alcoholic fatty liver from non-alcoholic steatohepatitis (NASH). Yet studies produced variable diagnostic performance. We aimed to provide summary estimates with increased … WebNov 30, 2024 · CK8/18 is a cocktail of two monoclonal antibodies. In Western blotting of A431 cell lysates, anti-CK8, clone EP17 recognizes a major band of 52 kDa …
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Cytokeratin 18 - an overview ScienceDirect Topics
Web4.15.4.4 Cytokeratin 18. CK18 is a cytoskeletal protein and the main intermediate filament family member expressed in the liver. The full-length form is liberated from necrotic cells, whereas a caspase-cleaved fragment is a product of the structural changes that occur during apoptosis. Soluble CK18 fragments can be detected in human serum with ... WebCK8/18 is a cocktail of two monoclonal antibodies. In Western blotting of A431 cell lysates, anti-CK8, clone EP17 recognizes a major band of 52 kDa corresponding to the expected … WebThe tumor cells were positive for CK 8/18, EMA and S100, showed focal staining for CK7, and were negative for CK20, CK 1/5/10/14 and CEA. On the basis of these results a diagnosis of parachordoma was favored. For comparison, an immunohistochemical analysis of five axial chordomas was also performed. The chordomas showed positivity for CK … fun wall calendars 2022