Cisplatin myopathy

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August undefined, 2024

WebDec 21, 2024 · On this basis, mitochondrial myopathies are a heterogeneous group of diseases mainly originating by the inability of mitochondria to sustain cellular energy demands due to structural and functional alterations of the … WebOct 6, 2024 · The following are common signs of cardiomyopathy: Trouble breathing when you’re active or resting. Some people might also need to sleep sitting up or with many pillows under their head to help them …

Cisplatin (Intravenous Route) Side Effects - Mayo Clinic

WebAug 8, 2010 · Cisplatin is one of the most effective anticancer agents widely used in the treatment of solid tumors. It is generally considered as a cytotoxic drug which kills cancer cells by damaging DNA and inhibiting DNA synthesis. How cells respond to cisplatin-induced DNA damage plays a critical role in deci … WebResults: Cisplatin-induced neuropathy was more similar to neuropathy in patients receiving oxaliplatin than in those receiving paclitaxel. The cisplatin and oxaliplatin groups … css 秒表

Cisplatin Cancer information Cancer Research UK

Ninety patients with progressive recurrent lymphoma were treated with a … WebCisplatin is a type of chemotherapy. It destroys quickly dividing cells, such as cancer cells. Find out more about how chemotherapy works How do you have cisplatin? You have cisplatin as a drip into your bloodstream (intravenously). Into your bloodstream You might have treatment through a long plastic tube that goes into a large vein in your chest. WebCase Report tolerance of chemotherapy and good response, 3 additional cycles of paclitaxel, bevacizumab, and cisplatin were planned. However, cisplatin Our patient is a 33-year-old, morbidly obese (BMI 55 mg/kg2), was dropped for the 6th cycle due to cisplatin toxicity. css 空两格

Cisplatin (Intravenous Route) Side Effects - Mayo Clinic

Cisplatin-Induced Ototoxicity: A Concise Review of the Burden ...

WebMay 19, 2024 · Cisplatin treatment may cause hyponatremia through SIADH, related to both higher secretion of and sensitivity to ADH ( 32 ). Nausea and vomiting, which are common side effects of platinum-derived chemotherapy, are … WebMar 23, 2015 · Myositis, an inflammation of muscle, can be caused by injury, infection, medications, toxins, exercise, or autoimmune disease. In this report we describe the … css 禁止点击穿透WebJan 1, 2024 · After entering the hair cells, cisplatin causes hair cell death via DNA damage, redox system imbalance, and mitochondrial and endoplasmic reticulum dysfunction, culminating in programmed cell death including apoptosis, necroptosis, autophagic death, pyroptosis, and ferroptosis. css 穿梭效果

"WebElectrolyte disturbance: Cisplatin can cause hypomagnesaemia, hypokalaemia and hypocalcaemia. The hypocalcaemia seems to occur in those with low serum magnesium secondary to cisplatin, so it is not … " - Cisplatin myopathy

Cisplatin myopathy

Cisplatin-associated neuropathy characteristics compared …

WebAll myopathy is characterized by muscle weakness, most commonly in the upper arms, shoulders, and thighs. Other general symptoms you may have with myopathy include: … WebDec 1, 2024 · A prospective study evaluating early effects of BEP chemotherapy (bleomycin, etoposide, cisplatin) exposure on brain structure assessed testicular cancer patients …

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WebMar 15, 2024 · Cisplatin is a bedrock of cancer management and one of the most used chemotherapeutic agents in the treatment of germ cell, lung, bladder, ovarian, and head and neck cancers. Approximately 500,000 patients diagnosed annually with these cancer types in the United States could be candidates for treatment with cisplatin. WebFeb 1, 2024 · Cisplatin may cause serious kidney problems. Tell you doctor right away if you have blood in urine, change in frequency of urination or amount of urine, difficulty in …

WebDec 1, 2024 · The ICCTF [ 4] recommends using the following criteria for determining cognitive impairment: ≥2 test scores ≤−1.5 standard deviations from the normative mean (or an appropriate control group) or one test score ≤−2.0 standard deviations. Importantly, the more tests administered, the higher the probability of finding cognitive impairment. WebOur patients received cisplatin before carboplatin and all developed a mild sensory neuropathy while taking cisplatin (one had Lhermitte’s sign). This neuropathy appeared …

WebJul 22, 2024 · Cisplatin is a potent and valuable chemotherapy agent used to treat a broad spectrum of malignancies. Renal tubular dysfunction and a cumulative impairment in kidney function, as manifested by a decline in the glomerular filtration rate (GFR), can be … WebApr 1, 2015 · Dermatomyositis (DM) and polymyositis (PM) are both types of idiopathic inflammatory myopathies (IIM) characterized by inflammation and weakness of proximal skeletal muscles. DM disease is presented with specific cutaneous signs. Myositis can affect various organs with extra muscular manifestations: lungs, heart, joints, and intestine [ 1 - …

WebNov 18, 2024 · Albers, J. et al. Interventions for preventing neuropathy caused by cisplatin and related compounds. Cochrane Database of Systematic Reviews (Online) . 2011 Feb …

WebApr 7, 2024 · Mitochondrial dysfunction affects cells with high energy needs such as neural, skeletal muscle, heart, and liver cells and plays a crucial role in type 2 diabetes, as well as Parkinson’s, Alzheimer’s diseases, ischemia, stroke, cancer, and age-related disorders. css 種類一覧WebAug 23, 2024 · Peripheral neuropathy — a nerve disorder that can cause weakness, numbness, pain, and tingling or a “pins and needles” feeling — is a common side … early childhood education virginiaWebJun 29, 2024 · Cisplatin-induced peripheral neuropathy (CIPN) is a frequent serious dose-dependent adverse event that can determine dosage limitations for cancer … early childhood education vacancyWebWhat Cisplatin Is Used For: Treatment of advanced bladder cancer, metastatic ovarian cancer, and metastatic testicular cancer. Testicular, ovarian, bladder, head and neck, esophageal, small and non-small cell lung, breast, cervical, stomach and prostate cancers. css 空白を作るWebCisplatin is a platinum-based agent whose nephrotoxicity is thought related to the chloride in the cis position. Cisplatin gains entry into tubular cells via uptake by the OCT-2 … css 穿梭特效WebMar 1, 2012 · In this paper, we examine the nature of ROS-induced damage on key cellular targets of oxidative stress. We also review evidence … css 空格间距WebDec 13, 2024 · The neurologic complications of platinum compounds (cisplatin, carboplatin, and oxaliplatin) and of biologic response modifiers and molecularly targeted agents (both orally administered and therapeutic monoclonal antibodies) are discussed elsewhere, as are strategies to prevent and manage CIPN. css 穿透属性