WebMar 10, 2024 · Other side effects of metformin can include: a runny nose. low blood sugar. excessive sweating. chest discomfort. headache. weakness. In rare cases, metformin can cause lactic acidosis, a serious ... WebOct 26, 2024 · Check with your doctor immediately if any of the following side effects occur while taking metformin / pioglitazone: More common Bladder pain bloody or cloudy urine difficult, burning, or painful urination frequent urge to urinate lower back or side pain swelling of the face, fingers, feet, or lower legs weight gain Less common
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